Publications

Twedell EL, Bair-Marshall CJ, Girasole AE, Scaria LK, Sridhar S, Nelson AB. Striatal lateral inhibition regulates action selection in a mouse model of levodopa-induced dyskinesia. bioRxiv [Preprint].

Creed RB, Harris SC, Sridhar S, du Lac S, Zee DS, Dunn FA, Bouvier G, Nelson AB. Tau P301S Transgenic Mice Develop Gait and Eye Movement Impairments That Mimic Progressive Supranuclear Palsy. bioRxiv [Preprint].

Zhuang X, Lemak J, Sridhar S, Nelson AB. Inhibition of Indirect Pathway Activity Causes Abnormal Decision-Making In a Mouse Model of Impulse Control Disorder in Parkinson’s Disease. biorxiv [Preprint].

Ryan MB, Girasole AE, Flores AJ, Twedell EL, McGregor MM, Brakaj R, Paletzki RF, Hnasko TS, Gerfen CR, Nelson AB. Excessive firing of dyskinesia-associated striatal direct pathway neurons is gated by dopamine and excitatory synaptic input. Cell Rep. 2024 Aug 27;43(8):114483.

Schor JS, Gonzalez Montalvo I, Spratt PWE, Brajak RJ, Stansil JA, Twedell EL, Bender KJ, Nelson AB (2022). Therapeutic deep brain stimulation disrupts movement-related subthalamic nucleus activity in parkinsonian mice. eLife, 11:e75253.

Nelson AB, Girasole AE, Lee H-Y, Ptáček LJ, Kreitzer AC. Striatal indirect pathway dysfunction underlies motor deficits in a mouse model of paroxysmal dyskinesia. J Neurosci, 2022.

McGregor MM, McKinsey GL, Girasole AE, Bair-Marshall CJ, Rubenstein JLR, Nelson AB (2019). Functionally Distinct Connectivity of Developmentally Targeted Striosome Neurons. Cell Reports, Volume 29, Issue 6, 1419-1428.e5

 

Schor JS and Nelson AB (2019). Multiple stimulation parameters influence efficacy of deep brain stimulation in parkinsonian mice. JCI, In Press.

 

McGregor MM and Nelson AB (2019). Circuit Mechanisms of Parkinson's Disease. Neuron, Volume 101, Issue 6, 1042-1056.

 

Ryan MB, Bair-Marshall CJ, Nelson AB (2018). Aberrant Striatal Activity in Parkinsonism and Levodopa-Induced Dyskinesia. Cell Reports, Volume 23 , Issue 12 , 3438 - 3446.e5

Girasole AE, Lum MY, Nathaniel D, Bair-Marshall CJ, Guenthner CJ, Luo L, Kreitzer AC, Nelson AB (2018). A Subpopulation of Striatal Neurons Mediates Levodopa-Induced Dyskinesia. Neuron, In Press.

Girasole, A. E., & Nelson, A. B. (2015). Probing striatal microcircuitry to understand the functional role of cholinergic interneurons. Movement Disorders : Official Journal of the Movement Disorder Society, 30(10), 1306–18. 

Girasole, A. E., & Nelson, A. B. (2015). Bridging the Gap: Muscarinic M4 Receptors Promote Striatal Plasticity in Health and Disease. Neuron, 88(4), 621–623.

Nelson AB, Kreitzer AC. Reassessing Models of Basal Ganglia Function, in press, Annual Reviews Neuroscience, 2014.

Nelson AB, Bussert TG, Kreitzer AC, Seal RP. Corelease of glutamate and acetylcholine by cholinergic interneurons onto fast spiking interneurons of the striatum. J. Neurosci, 2014, 34(26):8772-7.

Nelson AB, Hammack N, Seal RP, Kreitzer AC. Striatal cholinergic interneurons drive axo-axonic GABA release from dopamine terminals. Neuron. 2014 Apr 2;82(1):63-70.

Nelson AB, Hang GB, Grueter BA, Pascoli V, Luscher C, Malenka R, Kreitzer AC. Normal striatum-dependent behavior in dopamine receptor BAC trangenic mice. J. Neurosci 32(27): 9119-23, 2012.

Gittis A, Nelson A, Kreitzer A. Distinct roles of GABAergic interneurons in the regulation of striatal output pathways. J Neurosci, 2010.

Nelson AB, Gittis AH, du Lac, S. Decreases in CaMKII activity trigger persistent potentiation of intrinsic excitability in spontaneously firing vestibular nucleus neurons. Neuron 46: 623-631, 2005

Nelson AB, Krispel CM, Sekirnjak C, du Lac S. Long-lasting increases in intrinsic excitability triggered by inhibition. Neuron 40: 609-620, 2003.